Microfluidics & Point-of-Care Diagnostics Facility

Advanced Microfluidics for Diagnostics & Research

The Microfluidics Facility at Yenepoya Technology Incubator is dedicated to the design, fabrication, and testing of microfluidic devices, with a strong focus on developing affordable Point-of-Care Testing. Working in close collaboration with translational research (NanoMaterials Research Laboratory (NMRL) @ Yenepoya) and successful spin-offs like Papersens Pvt Ltd (incubated at YTI), we aim to bridge the gap between laboratory discoveries and practical diagnostic solutions.

We support the development of innovative diagnostic tools for clinically relevant biomarkers, addressing needs in areas such as old-age related issues, child and women's health, leveraging cost-effective and user-friendly technologies.

Point-of-Care Innovation Hub

Our facility specializes in creating affordable, portable diagnostic platforms that require minimal sample volumes and can be used in resource-limited settings.

Key Capabilities & Technologies

Device Fabrication

Our facility specializes in creating various types of microfluidic analytical platforms with different materials and fabrication techniques:

Microfluidic Paper Analytical Devices (μ-PADs)

Cost-effective paper-based platforms for point-of-care diagnostics

PDMS-Paper Hybrid Chips

Combining the advantages of both materials for enhanced functionality

Simple Photolithography

For creating precisely defined microfluidic channels and patterns

Detection Modalities

Electrochemical Detection

Highly sensitive detection methods for quantifying biomarkers with precision using techniques like amperometry, voltammetry, and impedance measurements.

Colorimetric Assays

Visual detection methods that produce color changes visible to the naked eye, ideal for field use and resource-limited settings.

Fluorescence-Based Detection

Advanced optical techniques for enhanced sensitivity in detecting low-abundance biomarkers.

Analytical Equipment

Potentiostats (CH Instrument, Zensor simulator) for electrochemical measurements

Vacuum Plasma Cleaner for surface modification and preparation

Spectrophotometers (UV-Vis, Fluorescence) for optical analysis

Microcentrifuges for sample preparation and processing

Access to advanced analytical tools (HPLC, GC-MS, ATR-FTIR) through shared facilities

Assay Development

Our team provides expertise in developing various detection methods:

  • Immuno-sandwich recognition assays for high specificity
  • Integration of nano-bioconjugates for enhanced sensitivity
  • Optimization of reaction conditions for reliable detection
  • Validation against reference methods and standards

Focus Areas

Our facility is focused on developing diagnostic solutions with these key attributes:

  • Rapid testing with minimal turnaround time
  • Cost-effective approaches for affordability
  • Portable platforms for point-of-care use
  • Eco-friendly materials and approaches
  • Small sample volume requirements
  • Non-invasive or minimally-invasive testing methods

Collaborate with our Microfluidics Facility to develop and translate your innovative diagnostic ideas into impactful point-of-care solutions. Our expertise and infrastructure can help bridge the gap between laboratory concepts and field-deployable diagnostic tools.

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